Co-design and Pilot Study in VR-based Physical Activity and Cognitive Training

Hong Kong University of Science and Technology

Status: Completed

Conditions: Alzheimer's Disease; Physical Activity; Digital Health Intervention; Reminiscence Therapy; Dementia; Co-design

Treatments: Device: A physical activity and reminiscence therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT06982170

MiM20220101

FS110 (Other Grant/Funding Number)

Details and patient eligibility

About

Physical activity and reminiscence therapy alone have been studied with no clear effectiveness in Alzheimer's disease, but their combined intervention remains unknown. The health sector is now advocating the use of multiple interventions in dementia care. Here, we aim to develop a physical activity and reminiscence therapy device and investigate its effectiveness in older adults with dementia. As there is no existing device for the oldest old, who typically have frailty and comorbidities, we need to first design and co-design a novel device and conduct pilot studies for its feasibility, perception, sustained adoption (adherence) and then preliminary efficacy (usually pilot or phase I, and often single arm).

Full description

To slow the progression of Alzheimer's disease (AD), we need essentially design and co-design the interventional device to be effective for intervention. And since the oldest group is at high risk of dementia and AD, we wanted to address the needs of this forgotten group. there is no existing device or equipment designed for their intervention. In addition, their ability to sustain physical activity is relatively short, around 5-10 minutes, far less than the duration of normal physical activity. Hence, we need to ensure that the device is well accepted and likely to be used by the target group. Then we need to test its effectiveness.

Enrollment: 50 patients

Sex: All

Ages: 60 to 110 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• people who aged above 60
• people who can pedal the usual rehabilitation bike
• people who are willing to attend this study

Exclusion criteria

• people who cannot cycle usual rehabilitation bike (assessed by care professionals)
• people who cannot finish MoCA,

Trial design

Primary purpose: Device Feasibility

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

50 participants in 1 patient group

Interventional group

Experimental group

Description:

participants who were recruited in this study, were

Treatment:

Device: A physical activity and reminiscence therapy