Coagulation Parameters During Pregnancy in Amniotic Fluid

Rambam Health Care Campus

Status: Unknown

Conditions: Pregnancy

Study type: Observational

Funder types: Other

Identifiers

NCT00458666

CoagulationAmnioticFluid_CTIL

Details and patient eligibility

About

Amniotic fluid embolism is a rare devastating thromboembolic event, which is probably caused by the entrance of amniotic fluid (AF) to the maternal circulation. While AF contains coagulation activators, their role during pregnancy has not been elucidated. The current study aimed to evaluate coagulation parameters in AF during human pregnancy.

Full description

Amniotic fluid embolism is a rare devastating thromboembolic event, which is probably caused by the entrance of amniotic fluid (AF) to the maternal circulation. While AF contains coagulation activators, their role during pregnancy has not been elucidated. The current study aimed to evaluate coagulation parameters in AF during human pregnancy.

Sex: Female

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Women undergoing amniocentesis during 15-35 weeks of gestation.

Exclusion criteria

• A history of venous thromboembolism
• Systemic disease i.e.; diabetes, hypertension, hypo or hyper-thyroidism,
• Anticoagulant treatment
• Abnormal embryo