Coagulation Profile in Patients Undergoing Coronary Angiography and Percutaneous Coronary Intervention (GlobalACT)

Centre of Postgraduate Medical Education

Status: Unknown

Conditions: Chronic Coronary Insufficiency; Smoking

Study type: Observational

Funder types: Other

Identifiers

NCT05336669

69/VII/Budaj/2021

Details and patient eligibility

About

The activated clotting time (ACT), global thrombosis test (GTT-3), platelet inhibition P2Y12 (VerifyNow) test and serum coagulation factors will be measured in patients undergoing coronary angiography (CA) and percutaneous coronary intervention (PCI).

Full description

The activated clotting time (ACT), global thrombosis test (GTT-3) and platelet inhibition P2Y12 (VerifyNow) test and serum coagulation factors will be measured in patients undergoing coronary angiography (CA) and percutaneous coronary intervention (PCI) - 20 smoking and 20 non-smoking.The measurements will take place: before coronary angiography (CA), 10 minutes after unfractionated heparin (HNF), 2h after CA, 6h after CA, 30 days after CA

Enrollment: 40 estimated patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients scheduled do CA >18 years old

Exclusion criteria

• pregnancy
• previous treatment with P2Y12 inhibitors, novel oral anticoagulants (NOAC) or warfarin acenocoumarol in last 24 hours

Trial design

40 participants in 2 patient groups

Non-smoking

Description:

Non-smoking patients undergoing coronary angiography or percutaneous coronary intervention

Smoking

Description:

Smoking patients undergoing coronary angiography or percutaneous coronary intervention