Coagulopathy in Cardiac Surgery

Mahidol University

Status: Completed

Conditions: Coagulopathy, Cardiac Surgery, Cardiopulmonary Bypass

Study type: Observational

Funder types: Other

Identifiers

NCT03475940

Si2018-2

Details and patient eligibility

About

Coagulopathy in cardiac surgery; a quaternary-care academic center experience

Objectives:

Primary:

To determine incidence of coagulopathy after cardiac surgery in Thai people To determine incidence of resternotomy for stop bleeding, morbidity and mortality

Secondary:

To identify risk factors which associated with non-red cell transfusion and coagulopathy

study decide: Retrospective chart review

Full description

Data to be collected:

Age*, gender* Body weight, height, body mass index* Underlying disease: DM, renal disease*, liver disease* Pre-op. Antiplatelet or anticoagulant* Pre-op coagulogram and platelet count* Emergency or elective surgery Resternotomy or not* Intraoperative blood component Intraoperative factor concentration Dose and timing of antifibrinolytic administration* CPB time* Postoperative body temperature*

*Possible risk factors for non-red cell transfusion

statistic: To assess the relationship between risk factors and non-red cell transfusion a univariate analysis was performed using an unpaired t-test and a Chi-square test.

For higher accuracy regarding the impact of single risk factors, a multiple logistic regression analysis was also performed.

Enrollment: 398 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age ≥ 18 years
• Schedule to cardiac surgery under cardiopulmonary bypass

Exclusion criteria

• Schedule for aortic surgery or complex congenital cardiac surgery
• Using ECMO before surgery
• Incomplete anesthetic record