Coconut Sugar Lowers Blood Pressure and Arterial Stiffness in Middle-aged and Older Adults

Ball State University

Status: Completed

Conditions: Aging; Blood Pressure; Arterial Stiffness

Treatments: Dietary Supplement: Coconut Sap Powder (CSP); Dietary Supplement: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT05645991

COCOZEN

Details and patient eligibility

About

The goal of this intervention is to determine the efficacy of coconut sap powder (CSP) to lower arterial stiffness and blood pressure in middle-aged and older adults. Participants will be randomized to the CSP arm or Placebo arm of the study. Primary endpoints include: aortic stiffness assessed by carotid-femoral pulse wave velocity, resting brachial and (non-invasive) carotid blood pressure, and carotid stiffness (e.g. Beta stiffness index, Carotid compliance, Elastic modulus, Distensibility).

Enrollment: 22 patients

Sex: All

Ages: 40 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Body mass index 18-35 kg/m2
• Brachial blood pressure <140/90
• Nonsmoker
• No known clinical disease, or suggestive signs or symptoms of clinical disease
• Free of alcohol or drug dependence

Exclusion criteria

• taking any anti-hypertensive, lipid lowering or other cardiovascular altering medications
• Known allergies to coconut or tree nuts (i.e., cashews, almonds, or pistachios)
• Engaging in vigorous intensity exercise

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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22 participants in 2 patient groups, including a placebo group

Placebo

Placebo Comparator group

Description:

Capsules containing aspartame (1.5 g/day) were taken orally once daily for 8 weeks.

Treatment:

Dietary Supplement: Placebo

Coconut Sap Powder

Experimental group

Description:

Capsules containing coconut sap powder (CSP; 1.5 g/day) were taken orally once daily for 8 weeks.

Treatment:

Dietary Supplement: Coconut Sap Powder (CSP)