CODP Imaging From a Dose Perspective

Universitätsmedizin Mannheim

Status: Completed

Conditions: Radiation

Treatments: Diagnostic Test: computed tomography

Study type: Observational

Funder types: Other

Identifiers

NCT03581110

UMannheim

Details and patient eligibility

About

The noncontrast-enhanced chest computed tomography (CT) is an emerging diagnostical tool in patient with chronic obstructive pulmonary disease (COPD). As shown in previous studies and pointed out by the Fleischner society, an additional scan in expiration reflects the pathophysiology of this complex disease better and extends the clinical information of the CT.

Nevertheless, this scan is leading to an increase in radiation dose. But currently it is unclear if this increased radiation dose is proportional to the additional clinical value when compared to inspiration-only protocols. Therefore, the aim of this study was to compare the organ specific radiation doses of a combined inspiration-expiration CT on a 3rd generation dual-source scanner with noncontrast-enhanced chest CTs of two clinical routine scanners. Therefore, the radiation doses of nearly 2000 chest CTs have been evaluated.

Enrollment: 1,957 patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• noncontrast-enhanced chest CT performed on one of the named devices
• imaging performed between August 2014 and September 2017
• CT protocol used as previously specified

Exclusion criteria

Trial design

1,957 participants in 3 patient groups

16-slice CT scanner

Description:

1426 patients that have received a noncontrast-enhanced chest CT on our 16-slice clinical routine CT scanner in inspiration only.

Treatment:

Diagnostic Test: computed tomography

2nd generation dual-source CT

Description:

320 patients that have received a noncontrast-enhanced chest CT on our second generation dual-source CT scanner in inspiration only.

Treatment:

Diagnostic Test: computed tomography

3rd generation dual-source CT

Description:

211 patients that have received a noncontrast-enhanced chest CT on our third generation dual-source CT scanner in inspiration and expiration.

Treatment:

Diagnostic Test: computed tomography