Coeliac Disease in the Nord-Trøndelag Health Study (HUNT)

Norwegian University of Science and Technology

Status: Completed

Conditions: Celiac Disease

Treatments: Diagnostic Test: Endoscopy and biopsy

Study type: Interventional

Funder types: Other

Identifiers

NCT04041622

2017/924

Details and patient eligibility

About

In this study, all citizen of Nord-Trøndelag County, Norway, above 20 years of age are invited to participate in a population-based health study, the HUNT study. Blood samples are drawn from the participants and assessed for celiac disease by a serological assay. Celiac disease is a chronic inflammatory disease of the small intestine due to dietary gluten in wheat, barley and rye. The diagnosis will be verified through endoscopic assessment and biopsies from the small intestinal mucosa. The aims of the study are 1) to establish the population-based prevalence of celiac disease; 2) to assess the consequences of the disease from patient reported outcomes, symptoms, deficiencies, and co-morbidity; 3) to study possible risk factors and environmental triggering events; 4) to identify genetic predictors and gene-environmental interactions.

Enrollment: 56,000 patients

Sex: All

Ages: 20+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Participants of the forth round of the HUNT study

Exclusion criteria

• None

Trial design

Primary purpose: Screening

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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56,000 participants in 1 patient group

Endoscopy and biopsy

Other group

Description:

Participants of the HUNT study with a positive serological assay for celiac disease are invited to attain a diagnostic endoscopy with duodenal biopsies

Treatment:

Diagnostic Test: Endoscopy and biopsy