Coffee Trial - Does Coffee Intake Reduce Postoperative Ileus After Elective Colectomy?

Heidelberg University

Status: Completed

Conditions: Colectomy

Treatments: Other: Postoperative coffee; Other: water

Study type: Interventional

Funder types: Other

Identifiers

NCT01079442

NNR-6

Details and patient eligibility

About

The purpose of the investigators study is to investigate the effects of coffee on the return of bowel function and appetite, length of hospital stay, and complications after elective open colectomy in a prospective randomized trial. The primary efficacy endpoint is time to first bowel movement.

Full description

Coffee is a popular beverage. Its effects on general well being, central nervous system and cardiovascular system are well known, but there is limited information regarding its effects on gastrointestinal function.

Enrollment: 80 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients scheduled for elective open or laparoscopic colectomy
• Age equal or greater than 18 years
• Informed consent

Exclusion criteria

• Participation in concurrent intervention trials
• Need for a stoma
• Known hypersensitivity or allergy to coffee
• Expected lack of compliance
• Impaired mental state or language problems
• change in surgical procedure

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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80 participants in 2 patient groups, including a placebo group

Treatment arm: coffee

Active Comparator group

Description:

coffee administration

Treatment:

Other: Postoperative coffee

Water arm

Placebo Comparator group

Description:

The control drink consists of 100 ml warm water

Treatment:

Other: water