Cogmed Training Effect in Hypertensive Patients With Cognitive Impairment

University of Sao Paulo General Hospital

Status: Completed

Conditions: Hypertension

Treatments: Other: Cogmed

Study type: Interventional

Funder types: Other

Identifiers

NCT02738034

CogDoc2016

Details and patient eligibility

About

Systemic arterial hypertension is a disease with high prevalence in several countries, including Brazil. Many studies have correlated hypertension with accelerated loss of cognitive function, especially executive functions. There is some evidence that working memory (WM) is compromised in these populations. However, some computerized training has been developed to rehabilitate the WM, and among them the investigators highlight the Cogmed. Thus, the aim of this study is to evaluate the effects of Cogmed training in the performance of WM and attention of hypertensive patients, as well as the impact of training in the structure and brain function.

Enrollment: 32 patients

Sex: All

Ages: 40 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Individuals of both genders, of any ethnicity
• Signing the consent form
• Access to computer with internet at home
• Inexperienced to computerized cognitive training
• Hypertensive pre-diagnosed
• Basic schooling of four years
• Cognitive impairment

Exclusion criteria

• Marked functional limitation
• Cognitive limitation or serious communication
• Severe neurological and psychiatric diseases
• Stroke history, head trauma or substance abuse

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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32 participants in 2 patient groups

Adaptive training group

Experimental group

Description:

The intervention group will be composed of hypertensive participants with cognitive decline that will be submitted to the training program (Cogmed) for approximately 10 weeks. Across training, task difficulty was adjusted as a function of individual performance.

Treatment:

Other: Cogmed

Active control Group

Active Comparator group

Description:

In the control group, hypertensive patient will be submitted to a set of online games available on the internet and previously determined. In this way, the control group will receive the same motivation, as well as will be engaged in computerized activities, in the same way as the experimental group. The difference is that these varied games do not provide any type of intense and adaptive training, at the same time as they do not stimulate any specific cognitive function.

Treatment:

Other: Cogmed