Cognition and Ultrasound

University of Minnesota (UMN)

Status: Enrolling

Conditions: Healthy Participants

Treatments: Device: Low-Intensity Focused Ultrasound (FUS or LIFU)

Study type: Interventional

Funder types: Other

Identifiers

NCT07220655

PSYCH-2024-33067

Details and patient eligibility

About

Our primary goal is to investigate the role of Low-Intensity Focused Ultrasound (LIFU) neuromodulation on deep brain targets, and its potential to improve cognition

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 18 years of age or older
• Speak English (as assessed by their ability to read/answer survey questions)
• May be required to score in the appropriate range on self-report measures

Exclusion criteria

• They have a neurological disorder which may impact their fMRI scan or cause their reaction to LIFU to differ from that of healthy adults.
• They take any psychoactive medication.
• They are unable to undergo fMRI scanning due to a contraindication such as claustrophobia, unremovable piercings, pregnancy, the presence of medical devices such as pacemakers, or a movement or sleep disorder.
• Are pregnant, or may have reason to believe that they are pregnant.
• They have a diagnosis of a psychiatric condition other than depression or anxiety

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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100 participants in 1 patient group

Low-Intensity Focused Ultrasound

Experimental group

Treatment:

Device: Low-Intensity Focused Ultrasound (FUS or LIFU)