Cognition Following Computer Assisted Total Knee Arthroplasty (Minimental)

Rothman Institute Orthopaedics

Status

Completed

Conditions

Embolism, Fat

Cognition

Treatments

Device: Total Knee Arthroplasty Implant (Scorpio®)

Study type

Observational

Funder types

Other

Identifiers

NCT00830986

RIUWHOZ 09-01

Details and patient eligibility

About

A significant number of patients experience postoperative cognitive changes following total joint arthroplasty. Among other causes, the mental status change may be the result of fat and bone marrow debris embolization. We hypothesized that the use of computer assisted total knee arthroplasty, which does not utilize intramedullary alignment rods, would produce less fat and bone marrow debris embolization and, hence, fewer mental status changes.

Full description

Inclusion criteria

Primary, cemented knee arthroplasty
Unilateral or bilateral TKA

Exclusion criteria

Patient is unable to speak English
Unable to read and write
Patient with history of psychiatric disorders (Depression, Schizophrenia, anxiety, bipolar dis.)
Patients with history of IV drug abuse
Previous history of dementia
Patients on mental status changing medications

Enrollment

100 patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

Primary, cemented knee arthroplasty
Unilateral or bilateral TKA

Exclusion criteria

Patient is unable to speak English
Unable to read and write
Patient with history of psychiatric disorders (Depression, Schizophrenia, anxiety, bipolar dis.)
Patients with history of IV drug abuse
Previous history of dementia
Patients on mental status changing medications