Cognitive and Neural Assessment Platform and Localized Norm for Macau Older Adults.

University of Macau

Status

Not yet enrolling

Conditions

Aging

Cognitive Change

Cognitive Impairment

Cognitive Decline

Cognitive Dysfunction

Cognition Disorders in Old Age

Study type

Observational

Funder types

Other

Identifiers

NCT06239922

0153/2022/A (Other Grant/Funding Number)

BSERE23-APP019-ICI

Details and patient eligibility

About

The current project is dedicated to creating a comprehensive cognitive and neural assessment platform and corresponding norms tailored specifically to the older adults in Macau.

Full description

The investigators will establish this assessment platform using a combination of methods, including interviews, surveys, and expert reviews.

Steps include adapting existing assessment methods to the Macau context, developing new cognitive and neural tasks, defining standardized procedures, seeking external expert input, conducting pilot tests, and validation processes, and refining both the platform and its accompanying manual.

Enrollment

300 estimated patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Must be a local adult resident of Macau
Age above 50 years for older adult cohort
Younger adults individuals above 18 will be included as control comparators

Exclusion criteria

History of neurological injury or disease
Current use of medications that affect brain function or blood flow
Contraindications to MRI scanning, such as the presence of an electric/mechanical implant or device (e.g., pacemaker)
Claustrophobia
Body weight over 300 lbs due to weight and physical constraints of the scanner (i.e., bore size limited to 55 cm)
Inability to provide informed consent
Pregnancy
Being under the legal age of adulthood (children)
Incarcerated individuals (prisoners)