Cognitive Behavioral Suicide Prevention for Psychosis: Aim 2

University of Michigan

Status: Completed

Conditions: Psychosis; Suicide

Treatments: Behavioral: Services as Usual (SAU); Behavioral: Cognitive Behavioral Suicide Prevention for psychosis (CBSPp)

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT05345184

HUM00211008

R34MH123609 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

Investigators will evaluate the feasibility and preliminary effectiveness of modified Cognitive Behavioral Suicide Prevention for psychosis (CBSPp) in comparison to services-as-usual (SAU) in a randomized controlled trial. Investigators will recruit adult clients receiving services at a community mental health (CMH) setting who have a schizophrenia spectrum disorder and recent suicidal thoughts or behaviors within 3 months of screening (n=60). Client participants will be screened, enrolled and randomized to the CBSPp or SAU group. A 4-wave design will include quantitative assessments at baseline (T1), 1-month after baseline (T2), 3-months after baseline (T3), and 5-months after baseline (T4) with in-depth qualitative interviews at T3 for a random sample of adults in the CBSPp group (n=10). Providers (n=12) will be trained to deliver CBSPp and be assessed from T1-T3 to evaluate the implementation process, including in-depth qualitative interviews at T3.

Enrollment: 51 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Schizophrenia Spectrum Disorder
• Suicide ideation and/or attempt within 3 months of screening
• Ability to speak and read in English
• 18 to 65 years of age

Exclusion criteria

• Requiring emergency care (e.g. imminent plan to harm self) as determined by trained research staff administering the Columbia-Suicide Severity Rating Scale (C-SSRS)
• Inappropriate for behavioral treatment according to own judgment in consultation with a treating clinician CMH
• Impaired capacity (cognitive capacity)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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51 participants in 2 patient groups

Cognitive Behavioral Suicide Prevention for psychosis (treatment group)

Experimental group

Description:

Cognitive Behavioral Suicide Prevention for psychosis (CBSPp) is a behavioral treatment and will be delivered in 10 weekly individual therapy sessions in addition to standard/current services.

Treatment:

Behavioral: Cognitive Behavioral Suicide Prevention for psychosis (CBSPp)

Services as Usual (SAU; comparison group)

Active Comparator group

Description:

Services as usual involve standard and current services that clients are eligible for receiving.

Treatment:

Behavioral: Services as Usual (SAU)