Cognitive Behavioral Therapy for Adolescent Binge Eating and Loss of Control Eating

Yale University

Status: Completed

Conditions: Eating Disorders in Adolescence; Overweight and Obesity; Binge Eating

Treatments: Behavioral: Cognitive-Behavioral Therapy for Adolescent Binge/Loss-of-Control Eating; Other: Control Condition

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT04088097

K23DK115893 (U.S. NIH Grant/Contract)

2000024926

Details and patient eligibility

About

This study will develop and test a cognitive-behavioral intervention for adolescents with binge/loss-of-control eating.

Full description

Youth who engage in binge eating or loss-of-control eating are at high risk for physical and mental health impairment, as well as excess weight gain. As there are few evidence-based treatments for adolescents with binge/loss-of-control eating, assessment and treatment have received minimal attention for adolescent patients. Among adults, cognitive-behavioral therapy (CBT) has a strong evidence base for binge-eating disorder. Adolescents have unique social, cognitive and emotional needs because of their developmental stage; unique treatment approaches are essential to meet these unique needs. This study will develop a new CBT treatment for adolescents with binge eating or loss-of-control eating (modifying adult CBT for binge-eating disorder, conducting interviews with adolescents about aspects of treatment that need to be modified, conducting an open series of patients who receive the active treatment). This study will also test the efficacy of the newly-developed CBT for adolescents with binge/loss-of-control eating versus a control group in a randomized controlled trial.

Enrollment: 50 patients

Sex: All

Ages: 12 to 17 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: To be included, adolescents must:

1. Be in the age range ≥12 years old and ≤17 years old;
2. Have a BMI that places them above the 85th percentile based on their age and sex;
3. Report 2 episodes of binge/LOC eating (feeling a loss of control while eating) per month for the past 3 months;
4. Be otherwise-healthy youth (i.e., no uncontrolled or serious medical conditions);
5. Read, comprehend, and write English at a sufficient level to complete study-related materials;
6. Be available for participation in the study for 7 months.

Exclusion Criteria: Prospective participants will be excluded if the adolescent:

1. Has a medical or psychiatric condition that would require hospitalization or intensive care (e.g., neurological disorder, psychotic disorders, suicidality);
2. Has a medical or psychiatric condition that would prohibit them from engaging in behavioral treatment or moderate physical activity (e.g., cardiovascular problems);
3. Has uncontrolled medical condition(s) (e.g., uncontrolled diabetes or hypertension);
4. Is pregnant or breastfeeding;
5. Is taking medication(s) or participating in treatment(s) that could influence weight or appetite;
6. Began taking hormonal contraceptives less than 3 months prior;
7. Has a developmental or cognitive disorder (e.g., autism spectrum disorder);
8. Has a concurrent feeding/eating disorder (e.g., bulimia nervosa); or
9. Is participating in another clinical research study.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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50 participants in 2 patient groups

Cognitive-Behavioral Therapy

Experimental group

Description:

Adapted Cognitive-Behavioral Therapy (CBT) for adolescents with binge eating or loss-of-control eating.

Treatment:

Behavioral: Cognitive-Behavioral Therapy for Adolescent Binge/Loss-of-Control Eating

Control Condition

Other group

Description:

Educational materials related to adolescent health and nutrition.

Treatment:

Other: Control Condition