Cognitive-behavioral Therapy for Generalized Anxiety Disorder in Primary Care

Karolinska Institute

Status: Completed

Conditions: Generalized Anxiety Disorder

Treatments: Behavioral: Intolerance of uncertainty therapy; Behavioral: Metacognitive therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT03621371

SLSO-2018/505-31/1

Details and patient eligibility

About

The feasibilty and preliminary comparative effectiveness of two methods of cognitive-behavioral therapy - metacognitive therapy and intolerance of uncertainty therapy - for primary care patients with generalized anxiety disorder is investigated in a pilot study using a randomized controlled design. Purpose of the study is to examine the feasibility of a full-scale randomized controlled trial. Research questions primarily concern recruitment, measurement, and adherence.

Enrollment: 64 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Primary diagnosis of generalized anxiety disorder
• Age 18 years or above
• Being able to understand and speak Swedish without interpreter support

Exclusion criteria

• Psychosis, bipolar disorder, severe depressive symptoms, risk of suicid, substance use disorder, intellectual disability
• Simultaneous psychological treatment
• If pharmacological treatment, it needs to be stable prior to and during treatment

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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64 participants in 2 patient groups

Metacognitive therapy

Experimental group

Treatment:

Behavioral: Metacognitive therapy

Intolerance of uncertainty therapy

Experimental group

Treatment:

Behavioral: Intolerance of uncertainty therapy