Cognitive-Behavioral Therapy for Irritability in Adolescents With High Functioning Autism Spectrum Disorder

Yale University

Status: Completed

Conditions: Asperger's Disorder; Pervasive Developmental Disorder (PDD-NOS); Autism Spectrum Disorder (ASD; Autism

Treatments: Behavioral: Cognitive-Behavioral Therapy (CBT) for Irritability

Study type: Interventional

Funder types: Other

Identifiers

NCT01631851

0102012121-B

Details and patient eligibility

About

In addition to the core symptoms, children and adolescents with Autism Spectrum Disorder (ASD) often exhibit disruptive behavior problems including irritability, tantrums, noncompliance, and aggression. This is a pilot study of Cognitive-Behavioral Therapy, also known as Anger Control Training, in adolescents with high-functioning ASD. CBT teaches children to recognize antecedents and consequences of problem behavior and to use emotion regulation and problem-solving skills to reduce irritability, aggression and noncompliance. This form of CBT has been well-studied in typically developing children with disruptive behavior and we are investigating if this treatment can be feasible and helpful, with appropriate modifications, for irritability and disruptive behavior in ASD.

Enrollment: 9 patients

Sex: All

Ages: 9 to 16 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• DSM-IV diagnosis of autistic disorder, Asperger's disorder, or PDD-NOS
• presence of disruptive behaviors such as irritability and anger outbursts
• IQ above 80
• Unmedicated or on stable medication

Exclusion criteria

• medical or psychiatric condition that would require alternative treatment

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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9 participants in 1 patient group

Cognitive behavior therapy

Experimental group

Treatment:

Behavioral: Cognitive-Behavioral Therapy (CBT) for Irritability