Cognitive Complaints in Obstructive Sleep Apnea

VieCuri Medical Centre

Status

Completed

Conditions

Cognition Disorders

Sleep Apnea Syndromes, Obstructive

Treatments

Behavioral: questionnaires and neuropsychological assessments

Study type

Observational

Funder types

Other

Identifiers

NCT02769663

ABR 37795

Details and patient eligibility

About

The study assesses cognitive complaints in newly diagnosed patients with obstructive sleep apnea with no medical-comorbity affecting cognition. Cognitive complaints will be compared to healthy controls matched on age, sex and educational level. Factors related to cognitive complaints will also be assessed, including anxiety and depressive symptoms, complaints of fatigue and sleepiness, quality of life, psychological coping strategies and objective measures of cognition. Patients starting treatment for sleep apnea (continuous positive airway pressure or mandibular repositioning device) will be reassessed on all measures after 6 months of treatment to study the impact of treatment as usual on cognitive complaints and its related factors.

Enrollment

180 patients

Sex

All

Ages

18 to 70 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

native Dutch speaker
estimated verbal-IQ of ≥80

Exclusion criteria

other sleep disorder than obstructive sleep apnea
substance or alcohol abuse (e.g. no more than three units of alcohol per day for males and no more than two units of alcohol per day for females
diagnosis of a psychiatric disorder
use of medication effecting cognition
neurological disease, diabetes mellitus, hypo- or hyperthyroidism or lung disease (as checked by verbal report and medical records)