Cognitive Effects of Citicoline in Men and Women With Age-Associated Memory Impairment

Kyowa Hakko Bio

Status

Completed

Conditions

Healthy

Treatments

Dietary Supplement: Citicoline supplement

Dietary Supplement: Placebo supplement

Study type

Interventional

Funder types

Industry

Identifiers

NCT03369925

BIO-1707

Details and patient eligibility

About

The objective of this trial is to determine the effects of citicoline on cognitive performance in healthy Men and Women with Age-Associated Memory Impairment compared to a placebo.

Full description

This study is a 12-week, randomized, double-blind, placebo-controlled trial of citicoline in healthy men and women with Age-Associated Memory Impairment. Cognitive assessments will be performed to determine whether citicoline administration with supportive memory, compared to placebo administration.

Enrollment

100 patients

Sex

All

Ages

50 to 85 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

male or female, 50-85 years of age
at least a high school diploma or the equivalent
self-reported memory loss
scores ≥24 on the Mini-Mental State Examination, ≥85 on the Kaufman Brief Intelligence Test, Second Edition, ≤5 on the Geriatric Depression Scale, and 4, 3, or 2 on the Spatial Span Test
no health conditions that would prevent him or her from fulfilling the study requirements on the basis of medical history and routine laboratory test results

Exclusion criteria

color blind
abnormal laboratory test results
major medical or neurological illness
female who is pregnant, planning to be pregnant during the study period
requiring treatment with a drug which might obscure the action of the study treatment