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Cognitive Effects of Transcranial Direct Current Stimulation in Older Adults

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Johns Hopkins University

Status

Completed

Conditions

Aging

Treatments

Procedure: transcranial direct current stimulation

Study type

Interventional

Funder types

Other

Identifiers

NCT01611103
15657-O

Details and patient eligibility

About

This research is being done to determine whether transcranial direct current stimulation (tDCS) can improve certain mental abilities. In this research, a 9 volt battery is used to deliver very weak electrical current to the surface of the scalp while participants complete cognitive tasks. Our aim is to find out whether tDCS will improve task performance in adults over the age of 55.

Full description

Participants enrolled into this study may be asked to do the following:

  • Grant permission for the researchers to view medical records associated with their language/cognitive difficulties (if applicable).
  • Complete a questionnaire, provide a health history, and take some pencil-and-paper tests of problem-solving and memory in order to verify eligibility to participate and to able to safely undergo the experimental procedures.
  • Complete several tasks (i.e., saying words out loud, naming objects, drawing designs, remembering lists of words, searching for images or letters, and/or completing puzzles) based upon a number of cognitive functions such as language, memory, vision, processing, and perception.
  • Wear electrodes that will be placed on the scalp with a large rubberized band. These electrodes will administer very weak electrical current (tDCS) from a 9 volt battery for 20 to 60 minutes.
  • Participate in several study conditions. The exact conditions and their order will be randomized. Under some conditions, participants may receive active stimulation (tDCS) and under other conditions, they may receive sham stimulation.
  • The experimental sessions will last approximately 2 hours and participants may be asked to have more than one testing session in a day or to return for additional sessions.

Enrollment

43 patients

Sex

All

Ages

55 to 79 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Over the age of 55
  • Right Handed
  • Native English speaker

Exclusion criteria

  • History of Seizures
  • Any implanted metal device or pacemaker
  • Appreciable deficits in hearing or vision
  • Greater than 1.5 standard deviations below demographically adjusted means on cognitive screen
  • Dementia or Mini Mental Exam below 24

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

Single Blind

43 participants in 2 patient groups

Sham Stimulation
Sham Comparator group
Description:
transcranial direct current stimulation that is ramped up and ramped down providing the sensation of tDCS without delivering the full amount of tDCS
Treatment:
Procedure: transcranial direct current stimulation
Anodal Stimulation
Experimental group
Description:
transcranial direct current stimulation using Anodal stimulation over the area of interest
Treatment:
Procedure: transcranial direct current stimulation

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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