Cognitive Hyper-performance - Effects of Stimulating Substances in Chess-players (CHESS)

K. Lieb

Status and phase: Completed; Phase 1

Conditions: Cognitively Healthy Subjects Influenced by Psychoactive Drugs

Treatments: Drug: Drugs use: methylphenidate; Drug: caffeine; Drug: Drug use: modafinil; Drug: placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT01834547

1234

Details and patient eligibility

About

Effects of caffeine, methylphenidate, modafinil and placebo on cognitive performance of chess players in chess games and neuropsychiatric standardized tests. We hypothesize that substances will change cognitive performance in chess players leading to changed results in chess games and neuropsychiatric tests.

Enrollment: 40 patients

Sex: Male

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• male
• 18-60 years old
• existence of ELO-number

Exclusion criteria

• physical diseases (e.g. diabetes mellitus, etc.) with necessity of using prescription drugs
• psychiatric diseases (e.g. psychosis, bipolar disorders, etc.) with necessity of using prescription drugs
• addiction of psychoactive substances
• smoker or quitter (< 5 years)
• use of more than 5 cups of coffee per day
• irregular day-night-rhythm (e.g. shift workers)

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Triple Blind

---

40 participants in 4 patient groups, including a placebo group

Methylphenidate

Experimental group

Description:

Methylphenidate

Treatment:

Drug: Drugs use: methylphenidate

modafinil

Experimental group

Description:

modafinil

Treatment:

Drug: Drug use: modafinil

caffeine

Experimental group

Description:

caffeine

Treatment:

Drug: caffeine

placebo

Placebo Comparator group

Description:

placebo

Treatment:

Drug: placebo