Cognitive Intervention to Improve Memory in Heart Failure Patients (Memoir-HF)

Indiana University

Status: Completed

Conditions: Heart Failure NYHA Class II; Heart Failure NYHA Class III; Heart Failure NYHA Class I

Treatments: Behavioral: Computerized Crossword Puzzles; Behavioral: Computerized Cognitive Training with Brain HQ

Study type: Interventional

Funder types: Other

Identifiers

NCT03035565

R01NR016116-01A1

Details and patient eligibility

About

Cognitive Intervention to Improve Memory in Heart Failure patients

Full description

A three arm randomized controlled trial of 276 heart failure patients.

Enrollment: 276 patients

Sex: All

Ages: 21+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• At least 21 years of age
• Understands English
• Has access to a telephone
• Hears normal conversation
• For patients with hearing aids, able to wear and hear through headsets
• Diagnosis of chronic heart failure, stage C, NYHA I, II or III
• Receiving guideline derived medical therapy
• Heart failure validated by echocardiography or other method in past 2 years
• Able to read a computer screen with or without glasses or lenses

Exclusion criteria

• History of drug or alcohol abuse or major psychiatric diagnosis present before the heart failure diagnosis
• Alzheimer or other dementia diagnosis or central nervous system degenerative disorder
• Terminal cancer
• Patients with baseline Montreal Cognitive Assessment (MoCA) score of less than 19

Supplement Eligibility: First 144 patients randomized in the parent trial.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: Single Blind

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276 participants in 3 patient groups

Computerized Cognitive Training Brain HQ

Experimental group

Description:

Computerized cognitive training intervention using Brain HQ initiated and continued 1 hour/day, 5 days/week for 8 weeks

Treatment:

Behavioral: Computerized Cognitive Training with Brain HQ

Computerized Crossword Puzzles

Active Comparator group

Description:

General cognitive stimulation puzzles intervention initiated and continued 1 hour/day, 5 days/week for 8 weeks

Treatment:

Behavioral: Computerized Crossword Puzzles

Usual Care

No Intervention group

Description:

No computerized cognitive intervention