Cognitive Intervention With Go and Chess in Early and Subjective Cognitive Decline (Cognichess)

University of Milano Bicocca

Status: Enrolling

Conditions: Mild Cognitive Impairment; Subjective Cognitive Decline

Treatments: Other: Chess classes; Other: Go classes

Study type: Interventional

Funder types: Other

Identifiers

NCT06281652

Cognichess

Details and patient eligibility

About

The goal of this clinical trial]is to evaluate if learning to play traditional board games could improve cognition in subjects with mild cognitive impairment and subjective cognitive decline. The main questions it aims to answer are:

• Do Go and Chess improve cognition?
• Is a game better than the other? Is the effect of both games on cognition synergistic?
• Do Go and Chess improve quality of life?
• Do Go and Chess improve mood?
• Do Go and Chess improve lifestyle?

Participants will be randomized to one of four groups:

• Group intervention with Go, once a week, for 12 weeks
• Group intervention with Chess, once a week, for 12 weeks
• Group intervention with Go and Chess, twice a week, for 12 weeks
• Control group

Enrollment: 80 estimated patients

Sex: All

Ages: 55+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis of mild cognitive impairment or subjective cognitive decline
• Willingness to participate in the board games classes
• Living within 20-minute driving distance from the center
• Signed informed consent

Exclusion criteria

• Prior knowledge of the the game rules (in case the subject knows one of the two, they can be randomized to the other one)
• Significant linguistic or sensory impairment (according to clinical judgment)
• Significant behavioral or psychiatric disturbances (according to clinical judgment)
• Significant medical comorbidities (according to clinical judgment)

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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80 participants in 4 patient groups

Go classes

Experimental group

Description:

Subjects randomized to a group intervention with Go lessons once a week for 12 weeks

Treatment:

Other: Go classes

Chess classes

Experimental group

Description:

Subjects randomized to a group intervention with Chess lessons once a week for 12 weeks

Treatment:

Other: Chess classes

Go & Chess classes

Experimental group

Description:

Subjects randomized to a group intervention with Go and Chess lessons twice a week for 12 weeks

Treatment:

Other: Chess classes

Other: Go classes

Control

No Intervention group

Description:

Subjects randomized to no intervention for 12 weeks