Cognitive-motor Training in Parkinson Disease

National Yang Ming Chiao Tung University

Status: Enrolling

Conditions: Parkinson Disease

Treatments: Other: Cognitive-motor training; Other: Conventional physiotherapy

Study type: Interventional

Funder types: Other

Identifiers

NCT06588439

NYCU113006AF2

Details and patient eligibility

About

Literature reviews showed the cognitive-motor training that combines cognitive tasks may enhance cognitive functions more effectively than individual interventions. Stepping-based cognitive-motor training has been shown to improve cognitive functions, balance, and gait performance in older adults. However, there is insufficient research evidence on the impact and correlation of this training mode on the walking ability, executive functions, and brain activity changes in people with PD. Therefore, this study is designed to investigate the effects of stepping-based cognitive-motor training on the walking ability, executive functions, and brain activity in people with PD.

Enrollment: 50 estimated patients

Sex: All

Ages: 40 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnoses of idiopathic Parkinson disease
• Stable dopaminergic medicine ≥ 2 weeks
• Able to walk 10 meters without aid
• Mini-Mental Status Examination ≥ 24 points
• No uncorrected visual or auditory disorders
• Education at least junior high school
• No other disease may affect balance

Exclusion criteria

• Other medical diagnoses of neurological, musculoskeletal, or cardiopulmonary disorders
• History of brain surgery (e.g. deep brain stimulation)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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50 participants in 2 patient groups

Cognitive-motor training group

Experimental group

Description:

Participants receive 16 sessions of cognitive-motor training.

Treatment:

Other: Cognitive-motor training

Control group

Active Comparator group

Description:

Participants receive 16 sessions of conventional physiotherapy.

Treatment:

Other: Conventional physiotherapy