Cognitive Processing Therapy vs. Sertraline for the Treatment of PTSD & SUD in Egyptian Patients

British University In Egypt

Status and phase: Completed; Phase 1

Conditions: Psychologic Manipulation

Treatments: Behavioral: Cognitive processing therapy; Drug: Sertraline; Other: Placebo Control

Study type: Interventional

Funder types: Other

Identifiers

NCT03469128

IRB Protocol CL-006 (Registry Identifier)

2016-2017PTBUE

Details and patient eligibility

About

The present research was aimed at comparing the effects of Cognitive Processing Therapy (CPT) with the effects of Sertraline in treating patients who have dual diagnosis PTSD & SUD. The present study examines the extent to which CPT is effective in treating PTSD symptoms for patients with PTSD and SUD.

Full description

Patients with co-occurrence PTSD & SUD disorders were grouped into 3 groups: first: Cognitive Processing Therapy (CPT) in which participants completed 12 sessions of CPT. Second: were treated by Sertraline. Third: a placebo control group.

Enrollment: 150 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients diagnosed with SUD

Exclusion criteria

• Patients diagnosed with other psychotic disorders

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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150 participants in 3 patient groups, including a placebo group

Cognitive processing therapy

Active Comparator group

Description:

Cognitive Processing Therapy (CPT) in which participants completed 12 sessions of CPT

Treatment:

Behavioral: Cognitive processing therapy

Sertraline

Active Comparator group

Description:

Patients with co-occurrence PTSD \& SUD disorders were treated by Sertraline.

Treatment:

Drug: Sertraline

Control group

Placebo Comparator group

Description:

Placebo Control group

Treatment:

Other: Placebo Control