Cognitive Rehabilitation in People With Metabolic Syndrome and Mild Cognitive Deficits

University of Ioannina

Status: Completed

Conditions: Cognitive Deficit; Metabolic Syndrome

Treatments: Other: Computerized cognitive program

Study type: Interventional

Funder types: Other

Identifiers

NCT05658354

27819

Details and patient eligibility

About

The goal of this clinical trial is to investigate the possibility of rehabilitation of mild cognitive deficits in people with metabolic syndrome. We aim to implement a cognitive training program on patients with metabolic syndrome and cognitive deficits, and examine its effectiveness both post-intervention (3 months) and after 12 months.

Researchers will compare two groups, the experimental group that will receive the computerized cognitive training and the control group that will receive no training.

Enrollment: 50 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 18 years or older
• Presence of metabolic syndrome according to the criteria of IDF (2005) or revised NCEP-ATP III (2005)
• Presence of mild cognitive deficit (-1.5 SD below age and education-adjusted normative mean) in previously administered neuropsychological tests of Trail Making test (Part A & B), Verbal Fluency test (animals and letter "x"), Logical Memory test (immediate and delayed recall)
• Written informed consent to participate

Exclusion criteria

• Presence of any serious neurological or psychiatric condition

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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50 participants in 2 patient groups

Computerized cognitive program

Experimental group

Description:

25 participants with metabolic syndrome and mild cognitive deficits; receive health advice using the World Health Organization's guidelines for Risk Reduction of Cognitive Decline and Dementia, and perform the computerized cognitive training program (BrainHQ) for 45 minutes per session, twice per week, over the 3-month intervention period.

Treatment:

Other: Computerized cognitive program

Control group

No Intervention group

Description:

25 participants with metabolic syndrome and mild cognitive deficits; receive health advice using the World Health Organization's guidelines for Risk Reduction of Cognitive Decline and Dementia.