Cognitive Remediation in Early Phase Psychosis

University of Oslo (UIO)

Status: Unknown

Conditions: Schizophrenia; Schizoaffective Disorder; Psychosis NOS

Treatments: Behavioral: Cognitive remediation

Study type: Interventional

Funder types: Other

Identifiers

NCT01546467

2010/1788 (REK)

Details and patient eligibility

About

The purpose of the study is to investigate the effect of a 30 hour cognitive remediation program for young patients with early phase schizophrenia spectrum disorders on cognitive, clinical and functional outcome measures. The remediation program is integrated with whatever active rehabilitation the participant is currently attending (school, work, day program etc).

Enrollment: 50 estimated patients

Sex: All

Ages: 18 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Early phase schizophrenia, schizoaffective disorder, psychosis NOS
• Less than 5 years since start of adequate treatment for psychotic disorder
• Age between 18-40
• Norwegian speaking (sufficiently to understand and complete assessments)

Exclusion criteria

• Traumatic brain injury
• Neurological disorder as determined by medical history
• IQ below 70

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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50 participants in 2 patient groups

Cognitive remediation

Experimental group

Description:

30 hour computer based cognitive remediation integrated in participants current rehabilitation program (school, work, day program)

Treatment:

Behavioral: Cognitive remediation

Wait list control group

No Intervention group

Description:

Participant continues in treatment/rehabilitation program as usual until 9 month assessment when participant receives the same cognitive remediation program as the experimental group.