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In this study, high-throughput screening and multi-omics (transcriptomics and proteomics) joint analysis technology will be employed to explore potential CTE/TES biomarkers (RNA and protein) in blood and its exosomes. Thereafter, these biomarkers will be combined with the reported TBI biomarkers to create a novel set of CTE/TES molecular diagnostic signatures. The findings may open a new avenue for the clinical diagnosis of the disease and the future research on its therapeutic strategy.
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Inclusion criteria
Athletes and patients with traumatic brain injury
Healthy Volunteers
Exclusion criteria
Athletes and patients with traumatic brain injury
Healthy Volunteers
120 participants in 3 patient groups
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Central trial contact
Xintong Ge, Doctor
Data sourced from clinicaltrials.gov
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