Cohort Study of Clinical and Neuroimaging Characteristics for BPPV Patients in China

X

Xi'an Jiaotong University

Status

Enrolling

Conditions

Vertigo
BPPV
Vertigo, Peripheral

Treatments

Device: Simultaneous cortico-spinal magnetic resonance imaging, Serum

Study type

Observational

Funder types

Other

Identifiers

NCT06228196
XJTU1AF2023LSK-566

Details and patient eligibility

About

The main objective is to analyze the abnormality of physical condition, mental health and blood examination of the patients with benign paroxysmal positional vertigo (BPPV). Besides, the investigators aim to establish a database of BPPV based on multimodal magnetic resonance imaging data in the brain to identify high-risk patients with residual dizziness (RD) and systematically establish the comprehensive assessment system for the precise diagnosis, treatment and recovery of RD, optimize the tactics of BPPV management in China.

Full description

This is an observational, longitudinal, and single-center study. Confirmed BPPV cases will complete the following programs before and after 1 and 6 months of treatment for exploring biological mechanism and predictive biomarkers of BPPV: 1) fill in the behavioral psychological scales, 2) submit blood samples at a local laboratory, 3) receive 3 times brain MRI scan. The healthy controls will complete the same programs as BPPV-group mentioned above only at the time of inclusion. The investigators will establish the brain MRI database containing neuropsychological scales and blood parameters of BPPV in China.

Enrollment

150 estimated patients

Sex

All

Ages

18 to 60 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Confirmed diagnosis of BPPV/Healthy subjects who have not had BPPV

Exclusion criteria

  • History of organic diseases in central nervous system and mental disorder, such as tumors, infections, depressive disorder, schizophrenia, etc. Claustrophobic

Trial design

150 participants in 2 patient groups

BPPV patients
Description:
Confirmed diagnosis of BPPV
Treatment:
Device: Simultaneous cortico-spinal magnetic resonance imaging, Serum
Healthy controls
Description:
Healthy subjects who have not had BPPV
Treatment:
Device: Simultaneous cortico-spinal magnetic resonance imaging, Serum

Trial contacts and locations

1

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Central trial contact

Yuan Wang, M.D.; Ming Zhang, PhD

Data sourced from clinicaltrials.gov

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