Colchicine Has Anti-diabetic Effect

Ministry of Health and Population, Egypt

Status: Completed

Conditions: Treatment Adherence

Treatments: Drug: Colchicine Tablets

Study type: Observational

Funder types: Other

Identifiers

NCT04377321

[e-mail]

Details and patient eligibility

About

Colchicine has antidiabetic effect and may be an option for type 2 diabetes management

Full description

Observational cohort prospective study with following of 150 newly diagnosed type 2 diabetes patients who were in 3 groups, had been monitored in a private clinic, each group 50 patients number, with 30 females and 20 males after written consent from all patients. The ages of all patients were between 35 and 55 years.

The aim of this study was to evaluate colchicine effect on A1C of newly diagnosed type2 diabetes compared to the metformin and control group on diet only.

The first group patients received colchicine 0.5twice daily for 6 months, the second group received metformin 1gm twice daily, the third group patients were on diet only. During the period of treatment, the investigators followed the patients if there were side effects of the drugs used. No side effects were monitored during the period of treatment except for gastric upset in some patients using metformin

Enrollment: 150 patients

Sex: All

Ages: 35 to 55 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• type 2 diabetes newly diagnosed age 35- 55 years

Exclusion criteria

• severe anemia hypothyroidism and hyperthyroidism moderate to severe liver or kidney disease

Trial design

150 participants in 3 patient groups

group 1 on cochicine

Description:

The first group patients received colchicine 0.5 twice daily for 6 months

Treatment:

Drug: Colchicine Tablets

group 2 on glucophage 1 gm twice daily

Description:

second group received glucophage 1gm twice daily for 6 months

Treatment:

Drug: Colchicine Tablets

group 3 control

Description:

the third group patients were on diet only for 6 months

Treatment:

Drug: Colchicine Tablets