Colchicine Levels in the Serum of FMF (Familial Mediterranean Fever) Patients

Sheba Medical Center

Status: Unknown

Conditions: FMF; Colchicine Toxicity; Colchicine Resistance

Treatments: Diagnostic Test: colchicine level measurement

Study type: Observational

Funder types: Other

Identifiers

NCT03210610

3997-17-SMC

Details and patient eligibility

About

in this study the investigators will measure the colchicine trough levels in 80 FMF patients taking stable doses of colchicine

Full description

80 FMF patients will enroll: 20 taking 1 mg colchicine a day 20 taking 1.5 mg colchicine a day 20 taking 2 mg colchicine a day 20 taking 2.5 mg colchicine a day one blood sample for trough colchicine levels will be taken. response to treatment, colchicine side effects and anthropometric data will be collected.

Enrollment: 80 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• constant colchicine levels

Trial design

80 participants in 1 patient group

FMF patients

Description:

fmf patients under a constant colchicine dose

Treatment:

Diagnostic Test: colchicine level measurement