COld Exposure With Controlled BReathing And Meditation in Patients With Multiple Sclerosis (COBRAMS)

Comenius University

Status: Active, not recruiting

Conditions: Multiple Sclerosis

Treatments: Combination Product: Wim Hoff method

Study type: Interventional

Funder types: Other

Identifiers

NCT06280573

MS1

Details and patient eligibility

About

The goal of this interventional study is to test the effect of the anti-inflammatory and neuroprotective effects of this supplementary training program that includes breathing exercises, cold exposure, and meditation in patients diagnosed with multiple sclerosis.

Researchers will compare the effect to control groups of MS patients without intervention.

Enrollment: 50 estimated patients

Sex: All

Ages: 18 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• RRMS diagnosed according to the official 2020 McDonald's criteria,
• age 18-55 years,
• MS duration up to 10 years,
• EDSS 1.0-5.5,
• willingness to participate

Exclusion criteria

• relapse or corticosteroid treatment within 3 months prior to study enrollment
• severe/unstable comorbidity

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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50 participants in 2 patient groups

intervention group

Experimental group

Treatment:

Combination Product: Wim Hoff method

control group

No Intervention group