Cold Snare Polypectomy for Small Bowel Polyps in Patients With Peutz-Jeghers Syndrome

Shandong University

Status and phase

Not yet enrolling

Phase 4

Conditions

Small Bowel Polyp

Peutz-Jeghers Syndrome

Treatments

Procedure: Cold snare polypectomy

Study type

Interventional

Funder types

Other

Identifiers

NCT06001476

2023-SDU-QILU-G002

Details and patient eligibility

About

This study aims to evaluate the feasibility and safety of Cold snare polypectomy for removing 5-9mm small intestinal polyps in patients with Peutz-Jeghers Syndrome (PJS),in order to provide some reference for clinical strategy of endoscopic treatment of small intestinal polyps in PJS patients, and may prolong the follow-up period of PJS patients Intervals.

Enrollment

40 estimated patients

Sex

All

Ages

8 to 60 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Age 8-60, male or female.
Diagnosed with Peutz-Jeghers Syndrome
Undergo enteroscopy for small bowel polypectomy.

Exclusion criteria

Absence of at least one study polyp (5-9mm stubby pedicle, wide pedicle and sessile small bowel polyps);
Be evaluated during enteroscopy for requiring surgical intervention (such as endoscopically difficult to handle giant polyps, intussusception, etc.)；
With more than 50 polyps ≥1cm found in this enteroscopy examination;
The polyp has been confirmed to be malignant by pathology, or highly suspicious of malignant transformation under endoscopy;
Receiving anticoagulant therapy during this treatment;
Unable or unwilling to provide informed consent.