Cold Snare Polypectomy Versus. Endoscopic Mucosal Resection

Asan Medical Center

Status: Unknown

Conditions: Colonic Polyp

Treatments: Other: EMR; Other: CSP

Study type: Interventional

Funder types: Other

Identifiers

NCT02476747

2015-0565

Details and patient eligibility

About

The investigators will investigate the efficacy of EMR compared to CSP in treatment of small colon polp (6~10mm).

One aim of this study was to investigate the necessity of EMR on resection of small colon polyp.

Full description

With sized polyp from 6mm to less than 10mm, it has been classified by the previous studies as a "small polyp".

Their potential for advanced neoplasia is usually size-dependent, but some recent studies found that, even in diminutive and small polyps, the rate of advanced neoplasia is relatively high about 9%-10%.

The investigators will prospectively investigate postprocedural outcomes, such as retrieval rate, procedural time, overall complication rate (Intraprocedural bleeding, postprocedural bleeding, and perforation) in colonoscopic polypectomy of small polyp between CSP and EMR.

Enrollment: 103 estimated patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All those over the age of 20 years who agree informed consent and who have at least one polyp of eligible size (6-10 mm)

Exclusion criteria

• (1) patients taking anticoagulant therapy during the past 1 week of the procedure, (2) known coagulopathy, (3) history of liver cirrhosis, chronic kidney disease, malignancy, inflammatory bowel diseases or significant infectious disease, (4) American Society of Anesthesiology class III or more, and (5) pedunculated polyps and polyps with malignant feature.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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103 participants in 2 patient groups

Cold snare polypectomy

Experimental group

Description:

CSP will be performed by closing the snare loop after positioning the open snare at the point of lesion.

Treatment:

Other: CSP

Endoscopic mucosal resection

Active Comparator group

Description:

EMR will be performed in the way of drawing the lesion into the loop of the snare and resecting followed by saline injection to the its margin.

Treatment:

Other: EMR