Collagen Injections for the Treatment of Acne Scars and Wrinkles

Northwestern University

Status and phase

Terminated

Phase 1

Conditions

Wrinkles

Acne Scars

Treatments

Procedure: Vehicle

Drug: Fibroblast Treatment

Study type

Interventional

Funder types

Other

Identifiers

STU67333

Details and patient eligibility

About

The purpose of this study is to find out if autologous (your own) fibroblast injections are effective for the treatment of acne scars and wrinkles.

Enrollment

4 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Age 18 or over
Bilateral acne scars or have moderate to severe wrinkles
Subjects in good health
Subjects has the willingness and the ability to understand and provide informed consent for the use of their tissue and communicate with the investigator

Exclusion criteria

Under 18 years of age
Pregnancy or lactation
recent Accutane use in the past 6 months
prone to hypertrophic and keloidal scarring
have excessively redundant skin in the treatment area or wrinkles longer than 20 cm total
have a history of autoimmune disorders, organ transplantation, cancer not in remission, active or chronic skin disease
have a history of basal-cell carcinoma
have previously received autologous fibroblast treatment
have undergone any confounding therapy in the lower two-thirds of the face within 1 year or any investigational treatment within 30 days.
have an allergy to collagen, bovine products, local anesthetics, gentamicin, or amphotericin B
subjects who are unable to understand the protocol or to give informed consent
subjects with mental illness