Collecting and Storing Samples of Blood From Patients With Pancreatic Cancer and Healthy Participants

Johns Hopkins Medicine

Status: Completed

Conditions: Pancreatic Cancer

Treatments: Other: This is a non-intervention study for all groups.; Other: study of socioeconomic and demographic variables

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT00898482

JHOC-J0533

JHOC-05042601

P30CA006973 (U.S. NIH Grant/Contract)

JHOC-J0533 CDR0000452792

Details and patient eligibility

About

RATIONALE: Collecting and storing samples of blood from patients with cancer and healthy participants to test in the laboratory may help the study of cancer in the future.

PURPOSE: This study is collecting and storing samples of blood from patients with pancreatic cancer and healthy participants.

Full description

OBJECTIVES:

• Establish a central pancreatic cancer specimen (including serum and peripheral blood lymphocytes) repository to serve as a resource for current or future scientific studies.
• Utilize the clinical database to perform clinicopathologic correlation with the results of those studies.
• Test new hypotheses as they emerge.

OUTLINE: This is a prospective study.

Blood is collected from patients with pancreatic cancer at baseline and then every 3-6 months for up to 2 years. All other participants have blood collected at baseline and complete questionnaires at baseline and then every 3-6 months for up to 2 years. Serum and peripheral blood lymphocytes obtained from the blood samples are frozen and stored.

PROJECTED ACCRUAL: A total of 200 patients and 200 other participants will be accrued for this study.

Enrollment: 88 patients

Sex: All

Ages: 18 to 120 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

DISEASE CHARACTERISTICS:

• Meets 1 of the following criteria:

  • Histologically confirmed pancreatic malignant neoplasm

  • Serologically or image-confirmed diagnosis of pancreatitis or nonmalignant pancreatic disease

  • Healthy, at-risk participant meeting the following criteria:

    • Smoker, diabetic, and/or has a family history of pancreatic cancer

  • Healthy participant (no history of cancer)

PATIENT CHARACTERISTICS:

• Not specified

PRIOR CONCURRENT THERAPY:

• Not specified

Trial design

88 participants in 3 patient groups

Healthy individuals

Treatment:

Other: study of socioeconomic and demographic variables

Other: This is a non-intervention study for all groups.

At risk individuals

Treatment:

Other: study of socioeconomic and demographic variables

Other: This is a non-intervention study for all groups.

Cancer patients

Treatment:

Other: study of socioeconomic and demographic variables

Other: This is a non-intervention study for all groups.