Collecting Blood and Tissue Samples From Family Members of Patients With Pancreatic Diseases, Pancreatic Cancer, and Melanoma

Mayo Clinic

Status: Active, not recruiting

Conditions: Familial Pancreatic Cancer

Treatments: Other: survey administration; Other: medical chart review; Other: biologic sample preservation procedure

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT00835133

CDR0000613097 (Registry Identifier)

R01CA097075-08 (U.S. NIH Grant/Contract)

355-06

Details and patient eligibility

About

RATIONALE: Collecting and storing samples of blood and tissue from family members of patients with cancer to test in the laboratory may help the study of cancer in the future.

PURPOSE: This clinical trial is collecting blood and tissue samples from family members of patients with pancreatic disease, pancreatic cancer, and melanoma.

Full description

OBJECTIVES:

• To collect clinical history, family history, and blood and/or tissue samples from family members of patients diagnosed with pancreatic diseases, pancreatic cancer, or melanoma.
• To learn whether inherited factors increase the risk of pancreatic diseases, pancreatic cancer, or other cancers.

OUTLINE: Study participants undergo collection of blood and/or tissue samples as well as survey data for inclusion in a familial data and tissue registry. Participants complete two baseline surveys regarding their personal, family, health, and environmental exposure histories and regarding their opinions on cancer and cancer screening. Patients also complete a follow-up survey at 1 year and undergo review of their medical records.

Enrollment: 1,122 patients

Sex: All

Ages: 18 to 120 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

DISEASE CHARACTERISTICS:

• Meets 1 of the following criteria:

  • Has at least 2 blood relatives with pancreatic cancer (both must be related)
  • Has at least 1 blood relative with pancreatic cancer and 1 with melanoma (both must be related)

PATIENT CHARACTERISTICS:

• Mentally competent and able to provide informed consent
• Able to understand and read English

PRIOR CONCURRENT THERAPY:

• Not specified