Collecting Ducts Carcinoma: in Depth Exploration and Biologically Driven Therapy (CICERONE)

Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

Status: Unknown

Conditions: Collecting Duct Carcinoma

Study type: Observational

Funder types: Other

Identifiers

NCT05372302

INT 12/21

Details and patient eligibility

About

• Collect a large number of samples with certain / suspected diagnosis of collecting duct carcinoma in order to confirm the diagnosis (centralized review) and standardize according to WHO 2016 criteria
• Build an extensive tissue bank (DNA and RNA extraction) aimed at defining the molecular taxonomy of the tumor through 1) transcriptomic analysis 2) gene expression profile
• Define specific molecular signatures

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥ 18 years
• Signature of consent (for patients enrolled in the prospective part of the study)
• Histological diagnosis of renal cell carcinoma of the Bellini collecting duct RCC

Exclusion criteria