Collecting Medical Information and Tissue Samples from Patients with Pancreatic Cancer or Other Pancreatic Disorders

Mayo Clinic

Status: Enrolling

Conditions: Hereditary Pancreatitis; Chronic Pancreatitis; Islet Cell Tumor; Pancreatic Disease; Acute Pancreatitis; Pancreatic Neuroendocrine Carcinoma; Pancreatic Cancer

Treatments: Other: medical chart review; Other: survey administration; Other: biospecimen collection

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT00830557

CDR0000613100 (Other Identifier)

354-06

P50CA102701-08 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

RATIONALE: Gathering medical information and collecting and storing samples of blood and tissue to test in the laboratory may help doctors develop better ways to screen people at risk for pancreatic cancer or other pancreatic disorders in the future.

PURPOSE: This clinical trial is collecting medical information and tissue samples from patients with pancreatic cancer or other pancreatic disorders.

Full description

PRIMARY OBJECTIVE:

I. To maintain a resource (bank) of biospecimens and data collected from individuals being seen clinically for pancreas conditions to facilitate the discovery and development of (but not limited to) biomarkers of risk (including genomic and proteomic) and early detection as well as novel targeted therapies for pancreatic diseases with a focus on pancreatic cancer.

OUTLINE: This is an observational study.

Patients undergo blood, saliva, and previously obtained leftover tissue sample collection on study. Patients also complete questionnaires and have their medical records reviewed on study.

Enrollment: 12,000 estimated patients

Sex: All

Ages: 18 to 120 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

• Known or suspected pancreas disease including:

  • pancreas adenocarcinoma
  • islet cell cancer
  • pancreatic cysts
  • pancreatitis (hereditary, acute, or chronic)

• Next of kin of deceased participant who did not complete participation before passing away

Exclusion Criteria:

• Under the age of 18
• Unable to provide informed consent
• Prison inmates

Trial design

12,000 participants in 1 patient group

Observational

Description:

Patients undergo blood, saliva, and previously obtained leftover tissue sample collection on study. Patients also complete questionnaires and have their medical records reviewed on study.

Treatment:

Other: biospecimen collection

Other: survey administration

Other: medical chart review