Collection of Autologous Blood Products by Double Erythrocytapheresis

Sanquin Research & Blood Bank Divisions

Status and phase: Completed; Phase 3

Conditions: Pre Operative Autologous Donation

Treatments: Procedure: whole blood collection; Procedure: eythrocytapheresis

Study type: Interventional

Funder types: Other

Identifiers

NCT00202475

PPO-C-02-15

Details and patient eligibility

About

The project will determine the advantages of double erythrocytapheresis in the collection of preoperative autologous erythrocytes as compared to the standard collections of whole blood. The study will assess the total reduction in the number of procedures required to obtain the preoperative units ordered by the surgeon. Also, successfulness of erythrocytaphereses versus classical whole blood collection for these patients will be compared.

Full description

The project will determine the advantages of double erythrocytapheresis in the collection of preoperative autologous erythrocytes as compared to the standard collections of whole blood. The study will assess the total reduction in the number of procedures required to obtain the preoperative units ordered by the surgeon. Also, successfulness of erythrocytaphereses versus classical whole blood collection for these patients will be compared.

Enrollment: 100 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Elective surgery

Exclusion criteria

• Malignancies
• Severe arrhythmias
• Congestive heart failure
• Recent angina
• Epileptic seizures in the last 3 months before collection

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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100 participants in 2 patient groups

1

Active Comparator group

Treatment:

Procedure: eythrocytapheresis

2

Active Comparator group

Treatment:

Procedure: whole blood collection