Collection of Blood for Multiple Collaborative Studies

University of California San Francisco (UCSF)

Status: Enrolling

Conditions: HIV

Study type: Observational

Funder types: Other

Identifiers

NCT01336855

H8211-04743-22

Details and patient eligibility

About

This study seeks to confidentially collect blood from HIV-positive individuals and HIV-negative controls to provide basic scientists with specimens for collaborative studies.

Full description

HIV positive patients are currently the focus of multiple collaborative research studies, both at UCSF and other institutions. The aims of these research projects include improving the understanding of etiology, immunology, epidemiology and treatment of HIV. There are numerous requests from basic scientists at UCSF for collaborative studies on specimens, especially for blood, saliva and urine samples. Specimens may be used to test such things as virus characteristics, genotyping and/or phenotyping resistance, plasma drug concentrations, immune function or evidence of complications of HIV disease. The samples may also be tested for genetic factors that may be related to the course of HIV disease

Enrollment: 2,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• HIV-1 antibody negative with similar characteristics to HIV-1 positive cohort
• HIV-positive subjects naive to antiretroviral therapy
• HIV-positive subjects stable on or off antiretroviral therapy for a minimum of 6 months
• Good venous access
• Able to provide informed consent

Exclusion criteria

• Hemoglobin < 9g/dl
• Hematocrit < 27%
• Active treatment for cancer
• Hospitalization or IV antibiotic use within the last 4 months
• Immunosuppressive therapy within the last 4 months

Trial design

2,000 participants in 2 patient groups

HIV Positive

Description:

HIV-1 positive subjects

HIV negative subjects

Description:

HIV-1 seronegative control group