Collection of Ocular Surface Impressions Cytology of the Living Eye From Patients With Dry Eyes or Limbal Stem Cell Deficiency. (ESSO)

Centre Hospitalier Universitaire de Saint Etienne

Status: Completed

Conditions: Eye Diseases

Treatments: Diagnostic Test: EYEPRIM

Study type: Observational

Funder types: Other

Identifiers

NCT06255301

2020-A00139-30 (Other Identifier)

19CH218

Details and patient eligibility

About

In order to develop innovative biomarkers for the diagnosis of two ocular surface pathologies, Dry Syndrome (DS) and Limbic Stem Cell Deficiency (LSCD), human cells from the ocular surface will be collected in order to test these biomarkers ex vivo.

Full description

To collect them, cytological fingerprints of the ocular surface are made using filter paper applied to the surface using a commercially available EC (European Conformity)-marked medical device, called EYEPRIM.

Enrollment: 300 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient affiliated or entitled to a social security scheme
• Age 18 years or older
• Presenting a Dry Syndrome, a limbic stem cell deficiency (clinical diagnosis) or another pathology (control).
• Signature of Consent

Exclusion criteria

• Major blepharospasm making examination impossible
• Pregnant women
• Breastfeeding women
• Protected Persons

Trial design

300 participants in 3 patient groups

Control group

Description:

150 patients with eye diseases other than dry eye syndrome or limbal stem cell deficiency will be included.

Treatment:

Diagnostic Test: EYEPRIM

dry eye syndrome

Description:

100 patients with dry eye syndrome will be included.

Treatment:

Diagnostic Test: EYEPRIM

limbal stem cell deficiency

Description:

50 patients with limbal stem cell deficiency will be included.

Treatment:

Diagnostic Test: EYEPRIM