Colon Capsule Endoscopy Versus Standard Colonoscopy in Ulcerative Colitis

University Hospital Muenster

Status: Terminated

Conditions: Ulcerative Colitis

Treatments: Procedure: Standard Colonoscopy; Device: PillCam Colon Capsule

Study type: Observational

Funder types: Other

Identifiers

NCT00837304

Med-B_CCE_vs_SC

Details and patient eligibility

About

The dimension of diagnostic procedures and therapy of chronic inflammatory bowel diseases largely depends on the degree of mucosal inflammation. Video colonoscopy is currently the gold standard in the evaluation of the mucosa in patients with Ulcerative Colitis (UC). PillCam Colon Capsule was developed by Given Imaging, Israel, as possible alternative imaging modality to evaluate mucosal changes in patients with UC. The colonic mucosa can be visualized and recorded by video while the colon capsule passes the colon.

Many patients suffering from UC ask their physician for possible alternative diagnostic imaging because they are uncomfortable with conventional colonoscopy.

The primary aim of the present study is to compare the new Pillcam Colon Capsule with standard colonoscopy with respect to assessing mucosal disease activity and localization of inflamed colonic mucosa in patients with known UC.

Enrollment: 14 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients over 18 years of age with
• known ulcerative colitis
• Indication for Standard Colonoscopy
• Informed Consent given by the patient

Exclusion criteria

• Patient has dysphagia
• Patient has congestive heart failure
• Patient has renal insufficiency
• Patient is known or is suspected to suffer from intestinal obstruction
• Patient has a cardiac pacemaker or other implanted electronical medical devices
• Patient is pregnant
• Patient has had prior abdominal surgery of the GI tract
• Patient has any condition, which precludes compliance with study and/or device instructions.
• Age less than 18

Trial design

14 participants in 1 patient group

UC

Description:

Patients with known ulcerative colitis

Treatment:

Procedure: Standard Colonoscopy

Device: PillCam Colon Capsule