Colonisation of Scalp by Topical Probiotic Micrococcus Luteus Q24

BLIS Technologies

Status: Completed

Conditions: Microbial Colonization

Treatments: Other: Active Comparator: Study Group B: Blis Q24 Serum at lower dose; Other: Active Comparator: Study Group A: Blis Q24 Serum at higher dose

Study type: Interventional

Funder types: Industry

Identifiers

NCT06166979

BLTCT2023/1

Details and patient eligibility

About

The purpose of this study is to evaluate the skin quality improvement and colonization efficacy following the application of probiotic Micrococcus luteus Q24 (BLIS Q24) to the scalp from a serum format in healthy adults.

Full description

This is a randomized double-blind baseline controlled pilot study with no crossover for the assessment of any changes to the microbial make-up of the skin (The local skin microbiome), detection of colonization by the probiotic bacterium (BLIS Q24) on the skin on the scalp and to evaluate the changes in skin quality parameters following topical application of probiotic in a serum format.

Enrollment: 20 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. In general, good health, is 18 - 80 years of age.
2. Practice good general body and hair hygiene.

Exclusion criteria

1. Have a history of autoimmune disease or are immunocompromised (have a weakened immune system).
2. Free from any scalp disease, active cut, or open wound
3. On hair loss treatment at least 2 months prior to sampling.
4. Have used anti-dandruff shampoos on the scalp and hair for at least 1 week prior to the trial.
5. On concurrent antibiotic or antifungal therapy or regular antibiotic or antifungal. use within the last 1 week.
6. People with allergies or sensitivity to dairy.

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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20 participants in 2 patient groups

Study Group A: Probiotic Micrococcus luteus Q24 serum (high dose)

Active Comparator group

Description:

Group A: Probiotic Micrococcus luteus Q24 serum (dose: 1e8 colony forming units per application)

Treatment:

Other: Active Comparator: Study Group A: Blis Q24 Serum at higher dose

Study Group B: Probiotic Micrococcus luteus Q24 serum (low dose)

Active Comparator group

Description:

Group : Probiotic Micrococcus luteus Q24 serum (dose: 1e6 colony forming units per application)

Treatment:

Other: Active Comparator: Study Group B: Blis Q24 Serum at lower dose