Color-dependent Melatonin Suppression

VA Palo Alto Health Care System

Status: Completed

Conditions: Melatonin

Treatments: Device: Light - standard; Device: Light - alternate

Study type: Interventional

Funder types: Other U.S. Federal agency

Identifiers

NCT02936674

IRB-10165

Details and patient eligibility

About

The purpose of this study is to examine the effects of complex, broad-band spectra light on the production of melatonin in humans.

Enrollment: 10 patients

Sex: All

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Stable health
• Normal color vision
• Normal hearing
• 18-35 years old

Exclusion criteria

• Significant depressive symptoms
• Pregnant or nursing
• Ocular pathologies
• Unstable or severe medical or psychiatric condition
• Extreme morning/evening type
• Regular smoker
• Use of medications that impact ocular function
• Alcohol use disorder
• Use of illegal drugs
• Irregular use of antihistamines, antidepressants, or sleeping medications

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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10 participants in 2 patient groups

Light 1

Experimental group

Description:

Light 1 will have an altered color composition as compared with a standard LED bulb.

Treatment:

Device: Light - alternate

Light 2

Active Comparator group

Description:

Light 2 will be a standard LED bulb.

Treatment:

Device: Light - standard