Colorado Adult Joint Assessment Scale (CAJAS) Validation

Bayer

Status: Completed

Conditions: Hemophilia A

Treatments: Other: Colorado Adult Joint Assessment Evaluation

Study type: Interventional

Funder types: Industry

Identifiers

NCT02284789

17819

Details and patient eligibility

About

To obtain evidence of content validity and reliability of the Colorado Adult Joint Assessment Scale (CAJAS), a clinician-reported outcome (ClinRO) measure, as adapted for use in a population of adults with moderate to severe hemophilia A treated with coagulation factor VIII (FVIII) therapy as secondary prophylaxis or episodic treatment.

Enrollment: 30 patients

Sex: Male

Ages: 18 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Male, 18 to 50 years of age
• Diagnosis of moderate to severe hemophilia A (documented <1-2% Factor VIII Concentration [FVIII:C])
• Willing to maintain current FVIII treatment regimen, whether prophylactic or on-demand, for the duration of the study

Exclusion criteria

• Routine need for wheelchair or routine need for two canes or crutches
• Diagnosis of another bleeding disorder such as von Willebrand Disease
• Known event that would interfere with the scheduled CAJAS evaluations (e.g., elective joint surgery, vacation)

Trial design

30 participants in 1 patient group

CAJAS evaluation

Other group

Treatment:

Other: Colorado Adult Joint Assessment Evaluation