Colorectal Cancer Associated Host and Microbiome Study

Tongji University

Status: Enrolling

Conditions: Colorectal Neoplasms

Study type: Observational

Funder types: Other

Identifiers

NCT03998644

CCAHMS

Details and patient eligibility

About

Recruit of healthy, precancer and colorectal cancer patients and record necessary information of demographic and also other messages. All the volunteers were asked to provide samples including stool, blood, urine and tissues. This protocol is performed with the permission of the ethics committee and all the participants were provided with informed consent.

Full description

Healthy subjects, precancer patients identified by colonoscopy or colonoscopy history and colorectal cancer patients identified by two independent pathologists will be enrolled. The demographic message including age, weight, height, drug history, family history of all participants will be recorded. Blood, stool and urine samples will be collected of all subjects. Tumor and adjacent tissue samples of colorectal cancer and precancer patients were collected, as well as normal tissue of healthy subjects.

Enrollment: 2,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria

1. individuals who were clear and signed the informed consent.
2. Male and female.
3. Age >18

Exclusion Criteria:

1. Any one who can not provide accurate information.
2. Any one who denies the study.
3. Younger than 18.

Trial design

2,000 participants in 3 patient groups

healthy

Description:

Subjects without colorectal disorders.

precancerous

Description:

Subjects with risk factors that may contribute to the carcinogenesis.

colorectal cancer

Description:

Patients who were identified by standard procedures to suffer with colorectal cancer.