COLPAC (RaDiCo Cohort) (RaDiCo-COLPAC)

Institut National de la Santé Et de la Recherche Médicale, France

Status: Active, not recruiting

Conditions: Low Phospholipid Associated Cholelithiasis

Study type: Observational

Funder types: Other

Identifiers

NCT05961826

C16-14

Details and patient eligibility

About

The goal of this observational study is to describe the various clinical, biological and radiological manifestations of LPAC syndrome, defined according to standard diagnostic criteria, or according to criteria extended to all symptomatic recurrent biliary lithiasis, and delineate the various possible evolutions.

Participants will be followed for 5 years and the inclusion sites will collect the necessary data at least once a year as part of routine patient care. A quality of life self-questionnaire will be completed by participants during these visits.

Enrollment: 650 estimated patients

Sex: All

Ages: 13+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Children or adults meeting the standard* or extended** diagnostic criteria for LPAC syndrome:

  1. First symptoms before the age of 40 years

  2. Radiological images compatible with the existence of intrahepatic lithiasis

  3. Recurrence of symptoms after cholecystectomy

     (*) standard criteria: symptomatic biliary lithiasis with at least 2 out of 3 criteria

     (**) extended criteria: symptomatic biliary lithiasis with 1 out of 3 criteria

     Exclusion Criteria:

• Patients who have undergone liver transplantation