Combination of Mixed Drugs vs Ibuprofen: a Randomized Clinical Trial (CoctailRCT)

Universidad Complutense de Madrid

Status: Completed

Conditions: Trismus; Pain; Swelling Lips &Amp; Face

Treatments: Procedure: Third molar extraction

Study type: Interventional

Funder types: Other

Identifiers

NCT07133360

2019-000736-27

Details and patient eligibility

About

Combination of vitamins and melatonine compared with the conventional use of ibuprofen after surgical third molar extraction

Enrollment: 12 patients

Sex: All

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy volunteers, non ibuprofen allergic, presence of impacted lower third molar

Exclusion criteria

• Diseases that avoid surgical intervention

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Triple Blind

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12 participants in 2 patient groups

Ibuprofen 400

Active Comparator group

Description:

Three ibuprofen 400 doses

Treatment:

Procedure: Third molar extraction

Coctail mixed Drugs

Experimental group

Description:

Vitamin D, Vitamin B and Melatonine at night instead Ibuprofen

Treatment:

Procedure: Third molar extraction