Combination of NHF and Nebulizer on Lung Function in COPD (AEROFLOW)

University of Leipzig

Status: Completed

Conditions: Chronic Obstructive Pulmonary Disease

Treatments: Device: Nebulizer; Device: Nasal high flow (NHF)

Study type: Interventional

Funder types: Other

Identifiers

NCT02885103

349-15-24082015

Details and patient eligibility

About

This study will prove to concept of effectiveness of NHF in combination with a nebulizer on reversibility of lung function in COPD patients.

Full description

Patients will inhale on day 1 with a nebulizer and on another day with combination of nebulizer an NHF in a randomised order.

Enrollment: 20 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• stable disease
• COPD

Exclusion criteria

• exacerbation
• right heart decompensation
• acute respiratory insufficiency
• acute disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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20 participants in 2 patient groups, including a placebo group

inhalation with nebulizer

Placebo Comparator group

Description:

inhalation with an nebulizer via mouth

Treatment:

Device: Nebulizer

inhalation with nebulizer and NHF

Active Comparator group

Description:

inhalation with combination of nebulizer and nasal high flow (NHF) via nasal cavity

Treatment:

Device: Nasal high flow (NHF)