Combination of Preoperative Gabapentin and TAP Blocks in Decreasing Postoperative Pain

State University of New York - Downstate Medical Center

Status and phase: Withdrawn; Phase 4

Conditions: Postoperative Pain

Treatments: Procedure: TAP Block; Drug: Gabapentin

Study type: Interventional

Funder types: Other

Identifiers

NCT02927405

926072

Details and patient eligibility

About

There is an increasing trend on decreasing narcotic use and maximizing efficiency in the perioperative care. There are no studies that have compared a TAP block versus a TAP block plus gabapentin for laparoscopic procures.This study will investigate if taking gabapentin and receiving a TAP block decrease post-operative morphine consumption. It will be a randomized controlled, double blind study, with 130 patients between 18-60 years; that will undergo laparoscopic GYN procedures. Secondary outcomes will look at the incidence of nausea, vomiting, and VAS (verbal analog scale) scores. This combination may be helpful because gabapentin will be used to decrease visceral and central pain, and TAP block will decrease somatic pain. Performing a multimodal approach may decrease narcotic consumption, adverse effects and improve pain management.

Sex: Female

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• female
• receiving laparoscopic GYN procedure
• between 18-60

Exclusion criteria

• are already taking gabapentin
• have diabetic neuropathy
• have a chronic pain syndrome
• take opioids at home
• are pregnant
• have kidney disease
• have an allergy to morphine

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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0 participants in 2 patient groups, including a placebo group

TAP Block plus placebo

Placebo Comparator group

Description:

Patients will only receive a TAP block procedure and then morphine consumption will be recorded.

Treatment:

Procedure: TAP Block

TAP Block plus gabapentin

Experimental group

Description:

Patients will receive a TAP block procedure and take pre-operative oral Gabapentin and morphine consumption will me recorded after surgery.

Treatment:

Procedure: TAP Block

Drug: Gabapentin